Figure 1

Study design. The subjects were divided into 2 groups, and after a 4-week pre-trial observation period, administered test capsules containing KB290 or placebo capsules not containing KB290 at 1 capsule/day for 4 weeks (consumption period I). Then, the capsule administration was suspended for 4 weeks in both groups (washout period), and the capsules opposite to those administered first were administered for 4 weeks (consumption period II).