Association of high complement and low immunoglobulins with the clinical symptoms of patients with fibromyalgia

Table 2 Immunological findings

	HC (n = 30) (mean ± SEM)	Sex- and age-matched FM (n = 36) (mean ± SEM)	Total FM (n = 41) (mean ± SEM)	p value*
CH50 (U/mL)	36.7 ± 1.4	52.9 ± 1.2 ¹⁾	52.6 ± 1.1 ²⁾	< 0.001
C3 (mg/dL)	102.1 ± 3.3	105.2 ± 3.0	104.0 ± 2.8	0.32
C4 (mg/dL)	21.6 ± 1.4	22.5 ± 1.0	22.3 ± 1.0	0.59
IgG (mg/dL)	1316.7 ± 61.2	1120.9 ± 44.7	1119.5 ± 41.5 ³⁾	0.033
IgM (mg/dL)	139.6 ± 10.6	107.4 ± 7.8	103.6 ± 7.3 ³⁾	0.022
hsCRP (ng/dL)	381.4 ± 96.3	813.4 ± 180.4 ⁴⁾	853.3 ± 193.8 ⁵⁾	0.020
ANA positivity (%)	3.3	8.3	7.3	0.40

1) n = 35, 2) n = 39, 3) n = 40, 4) n = 26, 5) n = 30
^* p values for comparison of HC and FM (n = 36) calculated with the Student t-test, Kruskal–Wallis test, or Pearson’s chi-squared test (ANA positivity)

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