Fig. 3

Visceral pain evaluated with visceromotor response. (A) Visceromotor response represented as electromyographic activity under graded pressure with 10, 20, 40, 60, and 80mmHg of CRD. (B) Difference in visceral sensitivity (counts/20 s) to colorectal distention with 10, 20, 40, 60, and 80 mmHg among all groups. *P < 0.05, **P < 0.01 MS + TNBS vs. controls, ⁺⁺P < 0.01 MS + TNBS vs. TNBS, ^#P < 0.05 MS vs. control. (C) Difference in visceral sensitivity (counts/20 s) to colorectal distention with 10, 20, 40, 60, and 80 mmHg between MS + TNBS rats and MS + TNBS + CP rats. *P < 0.05, **P < 0.01 vs. MS + TNBS