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  1. Chronic pain, particularly pain secondary to trauma, is often accompanied by a feeling of perceived injustice. A prevalent feeling of injustice often goes along with a prolonged rehabilitation and problematic ...

    Authors: Tilman Wolter and Barbara Kleinmann
    Citation: BioPsychoSocial Medicine 2025 19:7
  2. This study aimed to investigate whether psychological flexibility moderates the relationship between premenstrual dysphoric disorder (PMDD) symptoms and depression, anxiety, positive parenting, and negative pa...

    Authors: Junko Okajima and Isa Okajima
    Citation: BioPsychoSocial Medicine 2025 19:6
  3. The prevailing paradigm for the etiology of irritable bowel syndrome is that transient noxious events lead to long-lasting sensitization of the neural pain circuit, despite complete resolution of the initiatin...

    Authors: Ryoko Hasegawa, Kumi Nakaya, Motoyori Kanazawa and Shin Fukudo
    Citation: BioPsychoSocial Medicine 2025 19:5
  4. Premenstrual disorder (PMD), which includes premenstrual syndrome and premenstrual dysphoric disorder, has a complex pathogenesis and may be closely related to emotional cognition and memory. However, the mech...

    Authors: Kaori Tsuyuki, Miho Egawa, Takuma Ohsuga, Akihiko Ueda, Kazuki Shimada, Tsukasa Ueno, Kazuko Hiyoshi, Keita Ueda and Masaki Mandai
    Citation: BioPsychoSocial Medicine 2025 19:4
  5. Individuals with type 2 diabetes and eating disorders must change their eating behaviors, which are often influenced by psychological factors like depression and anxiety. To efficiently assess daily psychologi...

    Authors: Takeshi Horie, Ken Kurisu, Shuji Inada, Kenshi Kawahara, Yutaka Matsuyama, Hiroe Kikuchi, Yoshiharu Yamamoto, Toshimasa Yamauchi and Kazuhiro Yoshiuchi
    Citation: BioPsychoSocial Medicine 2025 19:2
  6. Fibromyalgia (FM) is a disease characterized by chronic widespread pain concomitant with various symptoms such as fatigue and anxiety. Although chronic inflammation has been implicated in the immunological abn...

    Authors: Satoshi Izuno, Masako Hosoi, Kozo Anno, Takahiro A. Kato, Nobuyuki Sudo and Kazufumi Yoshihara
    Citation: BioPsychoSocial Medicine 2025 19:1
  7. Recent studies have identified premenstrual disorders (PMDs) as a risk factor for postpartum depression. However, routine screening for preconception PMDs is not yet common in Japan. This study investigated th...

    Authors: Takuma Ohsuga, Miho Egawa, Kaori Tsuyuki, Akihiko Ueda, Maya Komatsu, Yoshitsugu Chigusa, Haruta Mogami and Masaki Mandai
    Citation: BioPsychoSocial Medicine 2024 18:24
  8. Psychosocial stress can induce various physical symptoms, including fever, which is a commonly seen symptom in pediatric practice. In cases of unexplained fever, psychogenic fever should be considered as a pot...

    Authors: Ayumi Okada, Yoshie Shigeyasu, Chikako Fujii, Chie Tanaka, Mana Hanzawa, Akiko Sugihara, Makiko Horiuchi and Hirokazu Tsukahara
    Citation: BioPsychoSocial Medicine 2024 18:23
  9. Low-grade systemic inflammation may be a key player in the immune activation that has been reported for mental health deterioration. We hypothesised that elevated serum levels of inflammatory cytokines increas...

    Authors: Hirohito Tsuboi, Hiroyuki Sakakibara, Yuuki Minamida-Urata, Hiromasa Tsujiguchi, Akinori Hara, Keita Suzuki, Sakae Miyagi, Masaharu Nakamura, Chie Takazawa, Takayuki Kannon, Jiaye Zhao, Yukari Shimizu, Aki Shibata, Aya Ogawa, Fumihiko Suzuki, Yasuhiro Kambayashi…
    Citation: BioPsychoSocial Medicine 2024 18:20
  10. A decreased glomerular filtration rate (GFR), estimated using creatinine (Cr– eGFR), is often found at the initial presentation of anorexia nervosa (AN). Its pathophysiology has been explained mainly by dehydr...

    Authors: Hiroyuki Miyahara, Yoshie Shigeyasu, Chikako Fujii, Chie Tanaka, Mana Hanzawa, Akiko Sugihara, Ayumi Okada and Hirokazu Tsukahara
    Citation: BioPsychoSocial Medicine 2024 18:19

    The Correction to this article has been published in BioPsychoSocial Medicine 2024 18:22

  11. Eating disorders can significantly impact the psychosocial functioning and physical health of adolescents. Early and effective treatment is crucial to prevent long-lasting and potentially devastating adverse e...

    Authors: Riccardo Dalle Grave and Simona Calugi
    Citation: BioPsychoSocial Medicine 2024 18:18
  12. Family caregivers, mostly parents, are greatly involved in the care of their children with end stage kidney disease (ESKD) globally. Yet, the experiences of these caregivers and the demands placed on them by t...

    Authors: Edward Appiah Boateng, Mabel Baaba Bisiw, Rosemary Agyapomah, Isaac Enyemadze, Joana Kyei-Dompim, Samuel Peprah Kumi and Dorothy Serwaa Boakye
    Citation: BioPsychoSocial Medicine 2024 18:17
  13. Intervention for older patients with cardiac disease and subthreshold depression (StD) may be an effective strategy to prevent the development of major depressive disorder. The subliminal priming with supralim...

    Authors: Masataka Sakimoto, Takumi Igusa, Takuya Kobayashi, Hiroyuki Uchida, Aya Fukazawa, Chihaya Machida, Hirokuni Fujii, Keisuke Sekine, Minori Kurosaki, Kenji Tsuchiya, Senichiro Kikuchi and Kazuki Hirao
    Citation: BioPsychoSocial Medicine 2024 18:16
  14. The autonomic nervous system plays a vital role in regulating physiological functions. Transcutaneous auricular vagus nerve stimulation (taVNS) is a method that provides insights into autonomic nerve modulatio...

    Authors: Ruri Katsunuma, Tsunehiko Takamura, Mitsuhiko Yamada and Atsushi Sekiguchi
    Citation: BioPsychoSocial Medicine 2024 18:15
  15. Patients with primary focal hyperhidrosis (hyperhidrosis) are known to have higher levels of anxiety induced by sweating than those who do not. However, in hyperhidrosis, no scale has been developed to measure...

    Authors: Sayaka Ogawa, Jun Tayama, Hiroyuki Murota, Masakazu Kobayashi, Hirohisa Kinoshita and Seiko Nakamichi
    Citation: BioPsychoSocial Medicine 2024 18:14
  16. Cognitive behavioral therapy for insomnia (CBT-I) is among the recommended non-pharmacological treatments for patients with insomnia. While there are multiple reports on the effects of CBT-I treatment, few stu...

    Authors: Ayana Hotchi, Wataru Yamadera, Masayuki Iwashita, Tomohiro Utsumi, Misato Amagai, Sakumi Nakamura, Takako Suzuki and Masahiro Shigeta
    Citation: BioPsychoSocial Medicine 2024 18:13
  17. Chronic Fatigue Syndrome patients suffer from symptoms that cannot be explained by a single underlying biological cause. It is sometimes claimed that these symptoms are a manifestation of a disrupted autonomic...

    Authors: Paloma Rabaey, Peter Decat, Stefan Heytens, Dirk Vogelaers, An Mariman and Thomas Demeester
    Citation: BioPsychoSocial Medicine 2024 18:10
  18. This study aimed to evaluate the association of COVID-19 preventive behavior and job-related stress with sleep quality among healthcare workers (HCWs). We conducted a cross-sectional survey using a questionnai...

    Authors: Muneto Izuhara, Kentaro Matsui, Ryo Okubo, Takuya Yoshiike, Kentaro Nagao, Aoi Kawamura, Ayumi Tsuru, Tomohiro Utsumi, Megumi Hazumi, Yohei Sasaki, Kazuyoshi Takeda, Hirofumi Komaki, Hideki Oi, Yoshiharu Kim, Kenichi Kuriyama, Takeshi Miyama…
    Citation: BioPsychoSocial Medicine 2024 18:8
  19. The coronavirus disease 2019 pandemic impacted both the physical and mental health of individuals. The resilience quotient (RQ) is an important factor that decreases mental health problems. This study aimed to...

    Authors: Tanyalak Sanphiboon, Napakkawat Buathong and Rattanaporn Chootong
    Citation: BioPsychoSocial Medicine 2024 18:7
  20. Assessment of extrapulmonary comorbidities is essential in chronic obstructive pulmonary disease (COPD). Deterioration of balance and increasing fear of falling are two of the most significant extrapulmonary m...

    Authors: seda karaca, Aysel Yildiz Özer, Sait Karakurt and Mine Gülden Polat
    Citation: BioPsychoSocial Medicine 2024 18:6
  21. Feeding and eating disorders are severe mental disorders that gravely affect patients’ lives. In particular, patients with anorexia nervosa (AN) or bulimia nervosa (BN) appear to have poor social cognition. Ma...

    Authors: Rio Kamashita, Rikukage Setsu, Noriko Numata, Yasuko Koga, Michiko Nakazato, Koji Matsumoto, Hiroki Ando, Yoshitada Masuda, Sertap Maral, Eiji Shimizu and Yoshiyuki Hirano
    Citation: BioPsychoSocial Medicine 2024 18:5
  22. In the context of the COVID-19 pandemic, pharmacists, despite their vital contributions, have faced significant challenges that have impacted their mental well-being, potentially leading to the development of ...

    Authors: Samar Younes, Souheil Hallit, Irfan Mohammed, Sarah El Khatib, Anna Brytek-Matera, Shadrach Chinecherem Eze, Kenneth Egwu, Rawshan Jabeen, Nebojša Pavlović, Pascale Salameh, Michelle Cherfane, Marwan Akel, Chadia Haddad, Randa Choueiry, Feten Fekih-Romdhane and Katia Iskandar
    Citation: BioPsychoSocial Medicine 2024 18:4
  23. In Europe, an herbal medicine containing peppermint oil is widely used in patients with irritable bowel syndrome (IBS). In Japan, however, no clinical evidence for peppermint oil in IBS has been established, a...

    Authors: Kei Matsueda, Shin Fukudo, Masayuki Ogishima, Yuki Naito and Soichiro Nakamura
    Citation: BioPsychoSocial Medicine 2024 18:3
  24. Postural tachycardia syndrome (POTS), a subset of orthostatic dysregulation, has been reported to be associated with anxiety. POTS can be classified into two forms based on the degree of tachycardia during ort...

    Authors: Midori Mizutani, Seiji Yoshida, Hidetaka Tanaka, Ginroku Yamawake, Atsuko Kubo, Yusuke Kurooka, Yoshitaka Ohta and Akira Ashida
    Citation: BioPsychoSocial Medicine 2024 18:2
  25. Previous studies have shown that patients with Coronavirus Disease 2019 (COVID-19) are likely to be affected by delirium and other psychiatric complications. We aimed to evaluate the relation between COVID-19 ...

    Authors: Tomoe Nishihara, Mao Shibata, Ayako Ohashi, Kazutoshi Hiyama, Takafumi Yamashita, Mika Kuroiwa and Nobuyuki Sudo
    Citation: BioPsychoSocial Medicine 2023 17:40
  26. The purpose of this study was to develop an internet-based Guided Self-Help CBT (iGSH-CBT) for Bulimia Nervosa (BN) / Binge Eating Disorder (BED) for Japanese patients and to test its feasibility.

    Authors: Noriaki Ohsako, Hiroshi Kimura, Tasuku Hashimoto, Yutaka Hosoda, Yosuke Inaba, Masaomi Iyo and Michiko Nakazato
    Citation: BioPsychoSocial Medicine 2023 17:37
  27. Fibromyalgia (FM) is a disease characterized by chronic widespread pain concomitant with psychiatric symptoms such as anxiety and depression. It has been reported that FM patients engage in pain catastrophizin...

    Authors: Satoshi Izuno, Kazufumi Yoshihara, Masako Hosoi, Sanami Eto, Naoki Hirabayashi, Tae Todani, Motoharu Gondo, Chie Hayaki, Kozo Anno, Akio Hiwatashi and Nobuyuki Sudo
    Citation: BioPsychoSocial Medicine 2023 17:36
  28. Visceral hypersensitivity in functional dyspepsia can be localized or widespread, and there is no simple method of assessment. Measuring interoceptive accuracy at different sites provides an assessment of perc...

    Authors: Kohei Yoshida, Tetsuya Abe, Kenji Kanbara, Kento Ueda, Yukie Saka-Kouchi and Hideaki Hasuo
    Citation: BioPsychoSocial Medicine 2023 17:35
  29. Physical activity (PA) provides substantial mental and physical health benefits for individuals of all ages. A limited number of long-term or longitudinal studies have investigated the association between psyc...

    Authors: Amrit Dhakal, Ken Kurisu, Sungjin Park, Kazuhiro Yoshiuchi and Yukitoshi Aoyagi
    Citation: BioPsychoSocial Medicine 2023 17:32
  30. In Asia, the proportion of patients with irritable bowel syndrome (IBS) with abdominal discomfort alone is significantly higher than that in western countries. The purposes of this study are to understand the ...

    Authors: Jia Lu, Yang Chen, Lili Shi, Xiaoqing Li, Guijun Fei, Ji Li, Aiming Yang and Xiucai Fang
    Citation: BioPsychoSocial Medicine 2023 17:31
  31. This study aimed to conduct a preliminary evaluation of the effects of 6-methylsulfinylhexyl isothiocyanate (6-MSITC) contained in wasabi rhizomes on fatigue and sleep and to examine its safety through overdos...

    Authors: Ryota Nakajima, Masanobu Kanou, Masahiko Tokushima, Yoshitaka Iwama and Kei Yamana
    Citation: BioPsychoSocial Medicine 2023 17:30
  32. The coronavirus disease 2019 (COVID-19) pandemic has increased the risk of individuals developing eating disorders and has exacerbated existing eating disorders. This observational study investigated the impac...

    Authors: Keisuke Kawai, Hisateru Tachimori, Yurie Yamamoto, Yuki Nakatani, Shinmi Iwasaki, Atsushi Sekiguchi, Yoshiharu Kim and Naho Tamura
    Citation: BioPsychoSocial Medicine 2023 17:29
  33. Authors: Kristine Sirevåg, S. H. Stavestrand, T. Sjøbø, T. B. Endal, H. M. Nordahl, E. Andersson, I. H. Nordhus, Å Rekdal, K. Specht, Å Hammar, A. Halmøy, J. Mohlman, H. Hjelmervik, J. F. Thayer and A. Hovland
    Citation: BioPsychoSocial Medicine 2023 17:28

    The original article was published in BioPsychoSocial Medicine 2023 17:25

  34. Noncardiac chest pain (NCCP) is persistent angina-like chest pain without cardiac origin that affects the patient’s health related quality of life (HrQoL), although it does not affect mortality. The effect of ...

    Authors: Irem Huzmeli and Aysel Yildiz Ozer
    Citation: BioPsychoSocial Medicine 2023 17:27
  35. Previous studies reported that the experience of maltreatment in childhood reduces subjective well-being in adulthood and that neuroticism is negatively associated with subjective well-being. However, the inte...

    Authors: Yota Fujimura, Akiyoshi Shimura, Chihiro Morishita, Yu Tamada, Hajime Tanabe, Ichiro Kusumi and Takeshi Inoue
    Citation: BioPsychoSocial Medicine 2023 17:26
  36. Generalised anxiety disorder (GAD) is a frequent and severe disorder among older adults. For older adults with GAD the effect of the recommended treatment, cognitive behaviour therapy (CBT), is reduced. Physic...

    Authors: Kristine Sirevåg, S. H. Stavestrand, T. Sjøbø, T. B. Endal, H. M. Nordahl, E. Andersson, I. H. Nordhus, Å. Rekdal, K. Specht, Å. Hammar, A. Halmøy, J. Mohlman, H. Hjelmervik, J. F. Thayer and A. Hovland
    Citation: BioPsychoSocial Medicine 2023 17:25

    The Correction to this article has been published in BioPsychoSocial Medicine 2023 17:28

  37. The Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) is a comprehensive psychosocial assessment proven useful for predicting the outcomes of organ transplantation that is expected to be ...

    Authors: Kosuke Takano, Hidehiro Oshibuchi, Sayaka Kobayashi, Junko Tsutsui, Satoko Ito, Rumiko Kamba, Rie Akaho and Katsuji Nishimura
    Citation: BioPsychoSocial Medicine 2023 17:24
  38. Orthostatic intolerance (OI), which is common in children and adolescents, negatively impacts their quality of life (QOL) due to physical symptoms that limit work, school, and daily activities. The purpose of ...

    Authors: Yoshie Shigeyasu, Ayumi Okada, Chikako Fujii, Chie Tanaka, Akiko Sugihara, Makiko Horiuchi, Takashi Yorifuji and Hirokazu Tsukahara
    Citation: BioPsychoSocial Medicine 2023 17:23
  39. The coronavirus disease 2019 (COVID-19) pandemic has affected the treatment system of medical institutions across the world. Studies of the populations and patients have reported mental health problems caused ...

    Authors: Yukari Yamanaka, Kazuhiro Yoshiuchi, Chiharu Kubo and Shin Fukudo
    Citation: BioPsychoSocial Medicine 2023 17:21
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